Publications by authors named "M Kouvari"

Background And Aims: Lipoprotein(a) (Lp(a)) is an emerging biomarker for cardiometabolic factors. We studied the role of Lp(a) in the full spectrum of metabolic dysfunction-associated steatotic liver disease (MASLD).

Methods: Three independent analyses were implemented using a multi-center, cross-sectional, liver biopsy-based study (n=332) (Study 1) and the UK Biobank prospective study (n=270,004) (Study 2, median follow-up=12.

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Article Synopsis
  • Research suggests that consuming fermented dairy products is linked to a lower risk of developing cardiovascular disease (CVD) over a 20-year period compared to non-fermented products.
  • A study in Greece involving over 3,000 participants showed that those who ate more than two servings of fermented dairy daily had a 1.5 times lower CVD risk.
  • The findings imply that dietary guidelines should encourage the consumption of fermented dairy products while cautioning against increased whole-fat dairy intake.
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Objectives: This study investigated the cross-sectional relationships of total choline intake with the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and its progression to liver fibrosis.

Study Design: The study used data on total choline intake, hepatic steatosis, and liver fibrosis from the cross-sectional 2017-2020 National Health and Nutrition Examination Survey, including 24-h dietary recalls and liver ultrasound elastography (FibroScan®).

Main Outcome Measures: Steatosis was defined as a controlled attenuation parameter score ≥ 285dB/m.

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Background & Aims: The available literature on the effect of apolipoprotein C-III (ApoC-III) inhibition in MASLD reveals inconsistencies. The aim of the present work was to examine levels of ApoC-III in the entire spectrum of metabolic-dysfunction associated steatotic liver disease (MASLD).

Methods: This is a multicenter study involving patients enrolled in two gastroenterology-hepatology clinics (Greece and Australia) and in a bariatric-metabolic surgery clinic (Italy), with liver biopsy before and after bariatric surgery or lifestyle modification.

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