Publications by authors named "M Koskiniemi"
Background: The triggering agent of multiple sclerosis is still unknown and many viruses, including human herpesvirus-6 (HHV-6), are under suspicion. In earlier study we found patients who had HHV-6 reactive OCBs in their CSF. We wanted to investigate whether HHV-6 has an active role in diseases with demyelination.
View Article and Find Full Text PDFBackground: Human parechoviruses (HPeVs) are RNA viruses associated with mild gastrointestinal and respiratory infections in children, but may also cause neonatal sepsis and CNS infections in infants. While the prevalence of HPeVs is known mostly among hospitalized populations, the knowledge of HPeV seroprevalence in the general population is poor.
Objectives: The aim of this study was to identify and compare the HPeV1-6 seroprevalence in Finnish and Dutch populations.
Article Synopsis
- Human parechoviruses are related to enteroviruses and can cause various health issues, including neonatal sepsis, respiratory problems, and gastrointestinal infections.
- This report discusses two cases of neonatal sepsis in October 2012, where HPeV4 infection was suspected as the cause.
- No other potential causes for the patients' illnesses were identified during the investigation.
Human parechoviruses (HPeVs) are RNA viruses associated mainly with mild gastrointestinal and respiratory infections in children and also cause neonatal sepsis and CNS infections. Human enteroviruses, close relatives of HPeVs, associate with the development of type 1 diabetes. In this study, the potential role of HPeV infections in promoting beta cell autoimmunity was investigated by analyzing stool samples of 54 prediabetic case and 134 healthy control children for the presence of HPeV RNA and comparing the derived infection frequencies.
View Article and Find Full Text PDFBackground: Human parechoviruses (HPeVs) are common viruses mainly infecting young children. Most infections are mild, but HPeV3 causes severe CNS infections in new-born infants.
Objectives: The aim was to study the epidemiology of HPeVs in Finnish general population in the period 1996-2007, with special emphasis on the different types circulating in Finland.