[The use of citoflavin in neonatology and pediatrics as a factor improving therapeutic efficacy in patients with central nervous system lesions of various etiology].

Possibilities of increasing the therapeutic efficacy in patients with perinatal central nervous system (CNS) lesions of hypoxic-ischemic and infectious etiology are considered. Some questions of pathophysiological features of hypoxic-ischemic CNS disorders in newborns and their connection with further cascade of pathological changes in organs and systems are highlighted. In this light, the authors substantiate the need for adequate and effective neuro- (cerebro-) protection by the timely antioxidant energy correction and antihypoxic therapy with cytoflavin.

[Hemodynamic characteristics of intracranial arteries and veins in chronic disturbances of blood circulation in vertebro-basilar system].

The study aimed at assessing functional state of cerebral hemodynamic in chronic disturbances of blood circulation in vertebro-basilar system using the data of neurological examination and radiological diagnostics received from the databases of Neurology Department of Central Clinic of Tbilisi State Medical University and Research Institute of Medical Radiology. The neurological data for 220 patients with cerebral vascular pathology (98 women, 132 men; mean age 62.2 +/- 10.

[Clinical, structural-functional and haemodynamic correlates of cerebral venous blood circulation disturbances].

Difficulties of liquor circulation as a result of cerebrospinal fluid absorption and venous drainage of the entire intracranial space, in particular in the presence of venous system abnormalities in the forms of hypoplasia or aplasia of venous sinuses, play an essentiale role in cerebral venous dyscirculation. The symmetric character of hydrocephaly in chronic insufficiency of cerebral blood circulation and strong dependence of chronic cerebrovascular insufficiency on passive congestion suggest that the latter is characteristic of the blood supply system in whole. The MPI analysis of 120 patients revealed signs of cerebral ischemic lesions in 72% of cases, i.

Vascular malformations of the brain venous system in children.

The vascular malformations of the central nervous system are an important cause of venous strokes in children. Arteriovenous malformations are characterized by direct anastomosis of arterial and venous channels without an intervening capillary bed. Vein of Galen malformation and cavernous malformation are a rare but important causes of mortality in neonates and infants.