Publications by authors named "M Kornmayer"
Objectives: The objectives of the study were to investigate the association between change in postoperative (post-op) tibial plateau angle (TPA) in dogs and cranial cruciate ligament disease (CCLD) after tibial plateau leveling osteotomy (TPLO) during 6 months on the post-op outcome.
Methods: The inclusion criteria included 60 dogs with CCLD treated with TPLO fulfilled. TPA measurements were taken immediately post-op and 6 months post-op by three observers, and change in TPA was calculated.
Tibial plateau leveling osteotomy (TPLO) has been commonly performed in dogs with cranial cruciate ligament disease (CCLD) since the introduction by Slocum and Slocum (1993). To reduce cranial tibial thrust the TPLO technique aims for a postoperative tibial plateau angle (TPA) of 5-6.5°.
View Article and Find Full Text PDFObjectives: This study aimed to investigate the recovery of limb function following a single intra-articular injection of platelet-rich plasma or hyaluronic acid in dogs with cranial cruciate ligament rupture treated with tibial plateau levelling osteotomy compared to dogs receiving no injection intraoperatively.
Materials And Methods: Sixty-two dogs with cranial cruciate ligament rupture, body weights of 20 to 40 kg, and no other orthopaedic conditions were enrolled in this prospective, randomised, double-blind, controlled study at the small animal clinic at LMU Munich. All dogs underwent tibial plateau levelling osteotomy.
Article Synopsis
- Researchers discovered that the transcription factor Nurr1 binds to a dopamine metabolite called 5,6-dihydroxyindole (DHI), which can help in designing new drugs targeting Nurr1.
- They screened a custom set of 14,000 DHI analogues and selected 24 candidates for testing, leading to the identification of three promising Nurr1 agonists with strong binding affinity.
- The study showed that these DHI derivatives effectively engage cellular targets and work well together, hinting at multiple binding sites that could be exploited for new therapeutic strategies involving Nurr1.
Objectives: The objective of the first part of this retrospective multicentre study was to identify and classify common calcaneal tendon (CCT) injuries in a study population of 66 cats.
Methods: The medical records of five different small animal referral centres and veterinary teaching hospitals between 2010 and 2020 were reviewed. In addition to patient-specific data, CCT injuries were characterised in detail.