[Chemiluminescent analysis of the functional state of cellular and humoral components of neutrophil phagocytosis system in recurrent herpes simplex].

Methods of chemiluminescent analysis of the opsonin-phagocytic system in patients with recurrent herpes simplex and of assessment of in vitro cell sensitivity to immunomodulating agents in the same test are described. The functional activity of neutrophils and opsonizing capacity of the blood sera of patients with herpes simplex infection were found appreciably reduced. Chemiluminescent analysis was found useful for the selection of individual immunocorrecting therapy.

[The use of immunostimulants for enhancing the immunogenicity of a herpes vaccine].

National immunostimulators and interferon inducers (poludan, ridostin, larifan, myelopide, vegetan) in combination with a commercial herpes vaccine (HV) were used for experimental immunization of mice. A 3-fold or greater rise of specific antibody titres was observed after a single immunization of intact BALB/c mice. In experiments in chronically infected animals a single inoculation of HV resulted in a 3-fold rise of specific antibody titres at 6 days postimmunization but not in later periods (20, 30 days).