Publications by authors named "M Koksal"
Objective: This study aimed to investigate whether human immunodeficiency virus (HIV) infection affects carotid and brachial artery wall thickness and whether measurement of this thickness contributes to traditional cardiovascular risk scoring in individuals living with HIV.
Materials And Methods: The patient group included people living with HIV who were followed up in the infectious disease clinic, and the control group included patients without HIV. In both groups, carotid artery intima-media thickness (cIMT) was measured with B-mode ultrasonography (B-USG).
Article Synopsis
- Researchers explored new anti-inflammatory drug options to reduce gastrointestinal side effects by synthesizing and testing various compounds, including disubstituted 1,3,4-oxadiazoles and 1,2,4-triazole derivatives.
- These compounds showed significant inhibition of nitrite production related to inflammation, with some displaying better effects than the commonly used drug indomethacin.
- Compound 6d emerged as the most effective at a low concentration, and its inhibitory mechanism was further supported by molecular docking studies with the iNOS protein.
Article Synopsis
- The study focuses on ensuring the correct placement of the applicator during intraoperative radiation therapy for brain metastases, as precise placement is crucial for effective treatment.
- Phantom tests were conducted to optimize image quality, leading to a clinical study where real-time cone beam computed tomography was used to guide the applicator's positioning based on acquired images.
- The results showed that image-guided therapy is feasible, as repositioning of the applicator was successfully done after detecting air gaps, indicating potential for improved treatment outcomes in neurosurgery.
Human pegivirus (HPgV) is transmitted through sexual or parenteral exposure and is common among patients receiving blood products. HPgV is associated with lower levels of human immunodeficiency virus (HIV) RNA and better survival among HIV-infected patients. This study aimed to investigate the prevalence of HPgV and determine its subtypes in HIV-infected individuals living in Istanbul, which has the highest rate of HIV infection in Türkiye.
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