Publications by authors named "M Kojoukhova"
Background: Idiopathic normal pressure hydrocephalus (iNPH) patients often develop Alzheimer's disease (AD) related brain pathology. Disease State Index (DSI) is a method to combine data from various sources for differential diagnosis and progression of neurodegenerative disorders.
Objective: To apply DSI to predict clinical AD in shunted iNPH-patients in a defined population.
Background: The Kuopio University Hospital (KUH) idiopathic normal pressure hydrocephalus (iNPH) cerebrospinal fluid (CSF) shunting protocol is described together with the initial outcomes of 175 patients with probable iNPH treated according to this protocol from a defined population. Our secondary aim was to display the variety of differential diagnoses referred to the KUH iNPH outpatient clinic from 2010 until 2017.
Methods: Patients were divided into four groups according to the prognostic tests: tap test (positive or negative) and infusion test (positive or negative).
Object: To investigate the incidence, comorbidities, mortality, and causes of death in idiopathic normal pressure hydrocephalus (iNPH).
Methods: A cohort of 536 patients with possible NPH from a defined population with a median follow-up time of 5.1 years, (range 0.
Background: Idiopathic normal pressure hydrocephalus (iNPH) is a late onset, surgically treated progressive brain disease caused by impaired cerebrospinal fluid dynamics and subsequent ventriculomegaly. Comorbid Alzheimer's disease (AD) seems to be frequent in iNPH.
Objective: We aim to evaluate the role of AD-related polymorphisms in iNPH.