Publications by authors named "M Koestenberger"

Metformin is the most commonly prescribed glucose-lowering drug for the treatment of type 2 diabetes. The aim of this study was to investigate whether metformin is capable of impeding the oxidation of LDL, a crucial step in the development of endothelial dysfunction and atherosclerosis. LDL was oxidized by addition of CuCl in the presence of increasing concentrations of metformin.

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  • Cardiac arrhythmias in newborns are uncommon, and electric countershock therapy is an effective treatment, yet there are no randomized controlled studies on its use in this age group.
  • *A systematic review was conducted to gather all studies on electric countershock therapy for neonates within 28 days of birth, focusing on its effectiveness and related outcomes.
  • *The review found that 113 neonates were treated with electric countershock, with atrial flutter being the most common arrhythmia; synchronized cardioversion was the primary method used and showed excellent results.
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  • * The study found that vortices (spiral flow patterns) in the aorta were mostly visible either in early diastole (when the heart fills with blood) or late systole (when the heart pumps), with specific measurements taken for each phase.
  • * The results, indicating good consistency in measurements, can provide baseline data for future studies on aortic flow in children with heart conditions.
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