Effects of photobiomodulation in mitochondrial quantity, biogenesis and mitophagy-associated genes in breast cancer cells.

In this article, we aim to evaluate the effects of photobiomodulation on mitochondria quantity, biogenesis, and mitophagy-associated genes in breast cancer (BC) cells. Both models were irradiated with a low-power infrared laser (880 nm, 150 mW) and amber LED (617 nm, 1500 mW), alone or simultaneously. We evaluated the mRNA expression of PINK1 and PGC-1α genes, and the mitochondrial number was assessed based on the ratio of mitochondrial DNA/genomic DNA (mtDNA/gDNA).

Development and psychometric testing of the school-life conflict scale (SLCS) among nursing students.

Background: Nursing students often face a heavy academic burden compared to students in other programs, possibly affecting their personal lives. However, a standardized scale assessing how academic demands interfere with the personal well-being in student nurses is lacking.

Objective: This study was conducted to develop and test the psychometric properties of the School-Life Conflict Scale (SLCS).

Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes.

Background: East African cichlid fishes have diversified in an explosive fashion, but the (epi)genetic basis of the phenotypic diversity of these fishes remains largely unknown. Although transposable elements (TEs) have been associated with phenotypic variation in cichlids, little is known about their transcriptional activity and epigenetic silencing. We set out to bridge this gap and to understand the interactions between TEs and their cichlid hosts.

Staged thoracoscopic internal traction approach for early repair of long-gap esophageal atresia (LGEA) with distal tracheoesophageal fistula (TEF).

Background: Long-gap esophageal atresia (LGEA) can complicate the management of esophageal atresia (EA) with or without a tracheoesophageal fistula (TEF). This series describes a short interval, staged, thoracoscopic internal traction approach for LGEA with distal TEF to manage complex anastomotic tension or an anatomically impossible esophageal anastomosis.

Methods: A retrospective review (2018-2024) was performed across four tertiary centers to identify patients with LGEA and distal TEF, managed with a staged, thoracoscopic internal traction approach.

Tactile, thermal and gustatory stimulation therapy in the treatment of post-stroke oropharyngeal dysphagia: a scoping review.

Purpose: To map in the literature the effects of tactile, thermal and/or gustatory stimulation on oropharyngeal dysphagia (OD) post-stroke.

Methods: This scoping review was conducted following the recommendations of PRISMA- ScR and the Joanna Briggs Institute (JBI), registered on the Open Science Framework and developed without language or publication period restrictions. Different databases and grey literature were used for article selection, and the PCC mnemonics constructed the research question ad eligibility criteria, thus including clinical studies involving adults (over 18 years old) diagnosed with OD post-stroke, who received tactile-thermal (TTS) and/or taste-gustatory (TGS) and/or tactile-thermal-gustatory stimulation for treatment, and had their effect measured through examinations, scales, or clinical assessment.