Publications by authors named "M Knuiman"
Background: Switching from a conventional to a high-sensitivity cardiac troponin (hs-cTn) assay enables detection of smaller amounts of myocardial damage, but the clinical benefit is unclear. We investigated whether switching to a hs-cTnI assay with a sex-specific 99th centile diagnostic threshold was associated with lower 1-year death or new myocardial infarction (MI) in patients with suspected acute coronary syndrome (ACS).
Methods: This pre-post study included nine tertiary hospitals in Australia.
Article Synopsis
- The study examines how the definition of myocardial infarction (MI) has changed since 2000, particularly focusing on the role of cardiac troponin tests in classifying acute coronary syndrome (ACS) subtypes using hospital data from Western Australia.
- Researchers analyzed hospital admission data and linked biomarker results for patients diagnosed with STEMI, NSTEMI, and unstable angina (UA) over a 14-year period, from 2002 to 2016.
- The findings reveal that trends in MI classifications from biomarker results matched those in ICD-coded data for STEMI and NSTEMI, showing a decline in STEMI rates and an initial increase in NSTEMI before a subsequent decline, while UA rates steadily decreased
Article Synopsis
- - The study analyzed smoking trends in Australia from 1910 to 2005, focusing on initiation and cessation rates among different age groups and genders to assess the impact of historical tobacco control policies.
- - Among nearly 30,000 participants, 56.8% reported having smoked, with young males showing consistently high initiation rates from 1910-1999, while young females saw a significant rise in smoking in the 1960s and 1970s.
- - The results revealed that while smoking cessation rates increased overall for ages 36-50, they plateaued for females and decreased for males post-1990, highlighting the varying effectiveness of tobacco control measures, particularly among younger individuals.
Introduction: Evidence of the benefits of arts engagement to community wellbeing has been mounting since the 1990s. However, large scale, quantitative, epidemiological studies of the "arts-healthy aging" relationship, or the types of arts older adults voluntarily choose to engage in as part of their everyday life, for enjoyment, entertainment or as a hobby (vs. therapy or interventions) are limited.
View Article and Find Full Text PDFPurpose: Non-adherence to heart failure (HF) medications is associated with poor outcomes. We used restricted cubic splines (RCS) to assess the continuous relationship between adherence to renin-angiotensin system inhibitors (RASI) and β-blockers and long-term outcomes in senior HF patients.
Methods: We identified a population-based cohort of 4234 patients, aged 65-84 years, 56% male, who were hospitalised for HF in Western Australia between 2003 and 2008 and survived to 1-year post-discharge (landmark date).