Publications by authors named "M Kleinjan"

Background: The COVID-19 pandemic negatively affected child and adolescent mental health and at the end of the pandemic (April 2022) child mental health had not returned to pre-pandemic levels. We investigated whether this observed increase in mental health problems has continued, halted, or reversed after the end of the pandemic in children from the general population and in children in psychiatric care.

Methods: We collected parent-reported and child-reported data at two additional post-pandemic time points (November/December 2022 and March/April 2023) in children (8-18 years) from two general population samples ( = 818-1056 per measurement) and one clinical sample receiving psychiatric care ( = 320-370) and compared these with data from before the pandemic.

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  • Adenoid cystic carcinoma is a rare type of cancer that can happen in the outer ear canal.
  • Sometimes, it can look like another type of skin cancer called sebaceous carcinoma, which makes it even rarer.
  • In this case, doctors used images and tests to confirm the diagnosis, showing it had special features that were unusual for this kind of cancer.
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Introduction: Polydrug use patterns among young adults using ecstasy vary, as well as their willingness to change them. Polydrug use patterns are likely associated with different adverse health outcomes. It is unknown whether polydrug use patterns of young adults who use ecstasy are similar in different countries.

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  • * Researchers used an optogenetic method to manipulate the arrangement of a protein called gephyrin, which affects the organization of inhibitory neurotransmitter receptors (GABA).
  • * This manipulation caused GABA receptors to move away from their ideal position, leading to decreased synaptic response, highlighting the importance of precise coordination between pre- and postsynaptic elements for effective synaptic function.
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Background: The COVID-19 pandemic has had an acute impact on child mental and social health, but long-term effects are still unclear. We examined how child mental health has developed since the start of the COVID-19 pandemic up to 2 years into the pandemic (April 2022).

Methods: We included children (age 8-18) from two general population samples ( = 222-1333 per measurement and  = 2401-13,362 for pre-covid data) and one clinical sample receiving psychiatric care ( = 334-748).

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