Publications by authors named "M Kitani"

Background: Progressive pulmonary fibrosis (PPF) is a critical concern in interstitial lung disease (ILD) management. The HAL score, which incorporates honeycombing (H), age >75 years (A), and serum lactate dehydrogenase >222 U/L (L), can predict acute exacerbations in patients with idiopathic interstitial pneumonia (IIP). This study aims to evaluate the predictive utility of the HAL score for PPF development.

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Severe fever with thrombocytopenia syndrome (SFTS) is known to cause gastrointestinal hemorrhaging; however, few reports have so far specified the site of the hemorrhaging or lesion characteristics. A 79-year-old man was admitted to the hospital with fever, anorexia, and diarrhea which was suspected to be due to gastroenteritis. On day 2, the patient developed hematemesis.

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Article Synopsis
  • This study investigates interstitial pneumonia with autoimmune features (IPAF) in patients with idiopathic interstitial pneumonia (IIP), aiming to identify serum biomarkers related to autoimmune characteristics and prognosis.
  • An analysis of 222 newly diagnosed IIP patients over three years revealed that high serum levels of CXCL10 were significantly associated with better lung function metrics and acute onset of symptoms, as well as a higher likelihood of IPAF classification.
  • The findings suggest that CXCL10 could serve as a valuable biomarker for evaluating the clinical course of IIP patients, highlighting its potential role in understanding disease progression and patient outcomes.
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Background: Patients with idiopathic interstitial pneumonia (IIP) have a favourable prognosis when they have interstitial pneumonia with autoimmune features (IPAF). However, precise IPAF-related findings from high-resolution computed tomography (HRCT) and lung histopathological specimens and the treatment response have not been fully determined. Therefore, this study was conducted to evaluate the relationship between findings on HRCT or lung histopathological specimens and the progression of interstitial pneumonia in patients with IPAF.

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