Publications by authors named "M Kingma"
Article Synopsis
- A new blood test interpretation tool has been created for clinical dementia practice, focusing on key biomarkers like P-tau181, GFAP, and NfL for more accurate diagnoses.
- The tool was developed using data from 1,199 plasma samples, with successful validation in independent cohorts showing high diagnostic accuracy for identifying different types of dementia.
- The final tool features visualizations like UpSet and density plots to help clinicians interpret results effectively in real-world settings.
Background: - Subgroup discovery (SGD) is the automated splitting of the data into complex subgroups. Various SGD methods have been applied to the medical domain, but none have been extensively evaluated. We assess the numerical and clinical quality of SGD methods.
View Article and Find Full Text PDFBackground: Airway pressure release ventilation (APRV) is a relatively new mode of ventilation in neonates. We hypothesize that APRV is an effective rescue mode in infants failing conventional ventilation and it is comparable in survival rates to rescue with high-frequency oscillatory ventilation (HFOV).
Methods: This is a 6-year retrospective cohort study of infants that failed synchronized intermittent mandatory ventilation (SIMV) and were rescued with either APRV or HFOV.
Background: Previous studies have shown that preoperative anaemia in patients undergoing cardiac surgery is associated with adverse outcomes. However, most of these studies were retrospective, had a relatively small sample size, and were from a single centre. The aim of this study was to analyse the relationship between the severity of preoperative anaemia and short- and long-term mortality and morbidity in a large multicentre national cohort of patients undergoing cardiac surgery.
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