Publications by authors named "M Kieslich"
Purpose: The impact of pediatric traumatic brain injury (pTBI) on health-related quality of life (HRQoL) in children and adolescents remains understudied. Short scales have some advantages in terms of economy and administration over longer scales, especially in younger children. The aim of the present study is to psychometrically evaluate the six-item German version of the QOLIBRI-OS-KID/ADO scale for children and adolescents.
View Article and Find Full Text PDFBackground: Ataxia telangiectasia is a multisystem disorder with progressive neurodegeneration. Corticosteroids can improve neurological functioning in patients with the disorder but adrenal suppression and symptom recurrence on treatment discontinuation has limited their use, prompting the development of novel steroid delivery systems. The aim of the ATTeST study was to evaluate the efficacy and safety of intra-erythrocyte delivery of dexamethasone sodium phosphate compared with placebo in children with ataxia telangiectasia.
View Article and Find Full Text PDFUntil recently, no disease-specific health-related quality of life (HRQoL) questionnaire existed for pediatric traumatic brain injuries (TBIs). In this revalidation study, the psychometric properties and the validity of the 35-item QOLIBRI-KID/ADO questionnaire in its final German version were examined in 300 children and adolescents. It is the first self-reported TBI-specific tool for measuring pediatric HRQoL in individuals aged between 8 and 17 years.
View Article and Find Full Text PDFArticle Synopsis
- The German Rivermead Post-Concussion Symptoms Questionnaire (RPQ) is an effective tool for measuring post-concussion symptoms in children aged 8-12 after experiencing a traumatic brain injury (TBI).
- A study examined the reliability and validity of the RPQ using a sample of 146 children, finding strong internal consistency and a better three-factor model for assessing symptoms compared to the original one-factor model.
- Findings indicate that the RPQ proxy ratings correlate well with other established measures (PCSI-P, PHQ-9, GAD-7), confirming its use as a reliable method for assessing post-concussion symptoms in children and adolescents.