The influence of age, gender, and race on the prevalence of depression in heart failure patients.

Objectives: The goal of this study was to determine the prevalence of depression in an out-patient heart failure (HF) population; its relationship to quality of life (QOL); and the impact of gender, race, and age.

Background: Most studies of depression in HF have evaluated hospitalized patients (a small percentage of the population) and have ignored the influence of various patient characteristics. Although reported depression rates among hospitalized patients range from 13% to 77.

Depression in patients with heart failure: physiologic effects, incidence, and relation to mortality.

Heart failure affects 4.8 million people in the United States. Patients depressed after myocardial infarction have increased morbidity and mortality.

Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-Indians.

Potential mechanisms accounting for the high cardiovascular death rates observed in Asian-Indians are dyslipidemia and insulin resistance. Polymorphisms in the APOC3 promoter (-455 T/C and -482 C/T) were frequently encountered in young Asian-Indians and they correlated with reduced concentrations of apolipoprotein A-I.

The effect of coenzyme Q10 in patients with congestive heart failure.

Background: Coenzyme Q10 is commonly used to treat congestive heart failure on the basis of data from several unblinded, subjective studies. Few randomized, blinded, controlled studies have evaluated objective measures of cardiac performance.

Objective: To determine the effect of coenzyme Q10 on peak oxygen consumption, exercise duration, and ejection fraction.