Publications by authors named "M Kell"

Background: The necessity of performing a sentinel lymph node biopsy in patients with clinically and radiologically node-negative breast cancer after neoadjuvant chemotherapy has been questioned. The aim of this study was to determine the rate of nodal positivity in these patients and to identify clinicopathological features associated with lymph node metastasis after neoadjuvant chemotherapy (ypN+).

Methods: A retrospective multicentre study was performed.

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The transcription factor Six2 plays a crucial role in maintaining self-renewing nephron progenitor cap mesenchyme (CM) during metanephric kidney development. In mouse and human, expression at single-cell resolution has detected Six2 in cells as they leave the CM pool and differentiate. The role Six2 may play in these cells as they differentiate remains unknown.

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Article Synopsis
  • - A 76-year-old male with a suspected urinary tract infection related to a chronic catheter showed no improvement with standard treatment, prompting further investigation.
  • - Blood cultures revealed a rare infection, and imaging identified a concurrent infectious splenic hematoma, which was confirmed through aspiration.
  • - The case report discusses both pharmaceutical and interventional treatment strategies used for this unusual infection, along with a timeline of the patient's care.
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