Identification of Potential Drug Targets in Erythrocyte Invasion Pathway of Plasmodium falciparum.

The erythrocyte invasion phase plays a critical role in multiplication, sexual determination, and drug resistance in Plasmodium falciparum. In order to identify the critical genes and pathways in the erythrocyte invasion phase, the gene set (GSE129949) and the RNA-Seq count data for the W2mef strain were used for further analysis. An integrative bioinformatics study was performed to scrutinize genes as potential drug targets.

Machine Learning-Based Surgical Planning for Neurosurgery: Artificial Intelligent Approaches to the Cranium.

Objectives: Artificial intelligence (AI) applications in neurosurgery have an increasing momentum as well as the growing number of implementations in the medical literature. In recent years, AI research define a link between neuroscience and AI. It is a connection between knowing and understanding the brain and how to simulate the brain.

Transition from surface phonon-polariton to surface phonon-plasmon-polariton by thermal injection of free carriers.

Surface phonon-polariton, surface plasmon-polariton, and surface phonon-plasmon-polariton are evanescent electromagnetic waves confined to the surfaces of different classes of materials, which gives each of them particular characteristics suitable for diverse applications. Natural or forced injection of free carriers in a dielectric may change the surface phonon-polariton into a surface phonon-plasmon-polariton. Understanding this effect provides an insight into the fundamental physics of surface electromagnetic waves on dielectrics and offers tools that can be used to develop new technologies.

Tuning electrical and thermal conductivities of the two-dimensional electron gas in AlN/GaN heterostructures by piezoelectricity.

We investigate the electrical and thermal conductivities of the two-dimensional electron gas (2DEG) confined in the quantum well formed at the heterojunction between a thin GaN layer and an AlN layer strained by an Al Ga N capping layer in the temperature range from 10 to 360 K. The experimental protocol developed to deduce from calorimetric and Hall-effect measurements at a variable temperature the critical characteristics and transport properties of the confined 2DEG is presented. It is found that, in the measured temperature range (10-360 K), the electrical conductivity of the 2DEG is temperature-independent, due to the predominance of scattering processes by interface defects.