Publications by authors named "M Katouli"

Recent genomic characterisation of translocating HMLN-1 isolated from mesenteric lymph nodes (MLNs) and blood of a patient with a fatal case of pancreatitis revealed the presence of a type 6 secretion system (T6SS) that was not present in non-translocating strains. This strain was also genomically similar to adherent-invasive (AIEC) LF82 pathotype. We aimed to identify the role of T6SS-1 in the pathogenesis of this strain and other pathogenic .

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The quality of aquatic ecosystems is an important public health concern [...

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The gastrointestinal tract's microbiota plays a crucial role in human health, with dysbiosis linked to the development of diseases such as inflammatory bowel disease (IBD). Whilst the pathogenic mechanisms underlying IBD remain poorly characterised, adherent-invasive (AIEC) has been implicated as a microbiological factor in disease pathogenesis. These strains show an enhanced ability to diffusely adhere to and invade intestinal epithelial cells, along with the ability to survive and replicate within macrophages.

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Article Synopsis
  • Isolated strains USC-21046 and USC-21048 were found in foaming coastal waters of Queensland, Australia, and showed typical characteristics of their genus, including specific polar lipids and fatty acids.
  • Phylogenomic analysis indicated that strain USC-21046 has 80.4% genome similarity with two reference strains, while USC-21048 has 83.6%, and both were distinguished by differences in physiological and chemotaxonomic traits.
  • The strains have genome lengths of approximately 6.9 million bp, with G+C contents of 65.2% and 67.8%, and are proposed as new species, with the names sp. nov. for USC-21046
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Introduction: The virulence-associated gene (VAG) repertoire and clonal organization of uropathogenic (UPEC) strains is influenced by host demographic, geographic locale, and the setting of urinary tract infection (UTI). Nevertheless, a direct comparison of these features among Australian and Turkish UPEC remains unexplored. Accordingly, this study investigated the clonal composition and virulence characteristics of a collection of UPEC isolated from Australian and Turkish UTI patients.

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