Publications by authors named "M Kastelein"

Introduction: Longitudinal monitoring of sometimes subtle waveform changes of the 12‑lead electrocardiogram (ECG) is complicated by patient-specific and technical factors, such as the inaccuracy of electrode repositioning. This feasibility study uses a 3D camera to reduce electrode repositioning errors, reduce ECG waveform variability and enable detailed longitudinal ECG monitoring.

Methods: Per subject, three clinical ECGs were obtained during routine clinical follow-up.

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Aim: To identify degenerative knee abnormalities using MRI and radiography 6 years after knee trauma, their relation with persistent knee symptoms and baseline prognostic factors.

Methods: Adults (18-65 years) with incident traumatic knee symptoms visiting their general practitioner were followed up for 6 years and underwent baseline MRI and 6-year follow-up MRI and radiography. Logistic regression was used to analyse associations between various degenerative abnormalities on 6-year MRI and radiography, persistent knee symptoms and baseline prognostic factors for knee osteoarthritis (OA) on 6-year MRI.

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Background: Traumatic knee symptoms are frequently seen, however, evidence about the course and prognostic factors are scarce.

Objectives: To describe the one and six-year course of traumatic knee symptoms presenting in general practice, and to identify prognostic factors for persistent knee symptoms.

Methods: Adolescents (≥12 years) and adults with traumatic knee symptoms (n = 328) from general practice were followed for six years with self-report questionnaires and physical examination.

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Background: There is a lack of knowledge about the course of knee instability in patients with traumatic knee disorders.

Objective: The aim of the study was to determine the course of traumatic knee instability during 1-year follow-up and to observe the treatment of knee instability by GPs.

Methods: Patients (n = 134) aged 18-65 years with traumatic knee disorders who consulted their GP within 5 weeks after trauma were enrolled in a prospective cohort study.

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Aims: (1) To assess the 1-year and 6-year courses of non-traumatic knee symptoms in adolescents and young adults presenting in general practice. (2) To identify prognostic factors for persistent knee symptoms at 1-year follow-up.

Methods: Adolescents and young adults (12-35 years; n=172) with non-traumatic knee symptoms were included in the cohort study by their general practitioner (GP) and followed for 6 years.

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