Publications by authors named "M Karthik Naik"

Article Synopsis
  • The study focuses on developing a rapid and accurate molecular detection system, called the PathCrisp assay, to identify infections and antibiotic resistance directly from culture samples.
  • The PathCrisp assay uses a combination of loop-mediated isothermal amplification and CRISPR-based detection, showing high sensitivity and specificity, particularly in detecting the New Delhi metallo-beta-lactamase (NDM) gene in clinical samples.
  • This novel assay provides results in about 2 hours without the need for complex equipment or extensive DNA purification, aiming to improve antibiotic treatment decisions in various healthcare settings.
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Objective This study aims to utilize the TriNetX database, a comprehensive global network, to improve our understanding of the frequency, demographic factors, and related comorbidities of surgical patients who develop venous thromboembolism (VTEs) events. Methods The global collaborative network in TriNetX was queried for all cases from January 1, 2017, through December 31, 2023. International Classification for Disease (ICD) diagnosis codes were used to define patient cohorts with deep vein thrombosis (DVT) of the upper or lower extremity or pulmonary embolism (PE).

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Graves' disease, a common autoimmune disorder, characteristically presents with upper eyelid retraction, causing significant functional and cosmetic concerns for affected individuals. The management of Graves' upper eyelid retraction has evolved significantly over recent years, with various surgical and non-surgical interventions. An ideal procedure is predictable and easily repeatable.

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Interlaminar shear strength (ILSS) and compressive strength are two of the most critical properties of carbon fiber-reinforced polymer (CFRP). In this report, three types of epoxy resins-4,4'-diaminodiphenylmethane epoxy resin (AG-80), bisphenol A epoxy resin (E-1NT), and novolac epoxy (EPN)-were studied. E-1NT is characterized by low viscosity and low cost but exhibits poor mechanical properties, while AG-80 offers better wetting with carbon fiber.

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Background: Patients with autosomal dominant polycystic kidney disease (ADPKD) represent >10% of patients awaiting kidney transplantation. These patients are prone to potentially severe urinary tract (UTI) and liver cyst infections after transplantation. Whether such infections compromise outcome is unclear.

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