Publications by authors named "M Karthik"

Article Synopsis
  • Pseudomonas aeruginosa is highly resistant to antibiotics due to intrinsic and acquired mechanisms, primarily utilizing Pseudomonas-derived cephalosporinase (PDC) and serine Ambler class C β-lactamases through the AmpC gene system.
  • * A study analyzed 111 P. aeruginosa isolates from India, identifying the ESAC allele PDC-447 as the most prevalent variant, particularly among carbapenem-resistant strains, while also noting other significant variants like PDC-398 and PDC-397.
  • * Genetic mutations in the PDC enzyme, such as T105A in the H-helix region, were linked to increased antibiotic resistance, emphasizing the complexity of resistance mechanisms and
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Objectives: To characterize the inflammatory cytokine profiles in children with TB in the presence and absence of SARS-CoV2 seropositivity.

Methods: This study evaluated cytokine responses in two groups of children with TB: CoV2+ (TB and SARS-CoV2 seropositive) and CoV2- (TB and SARS-CoV2 seronegative). Each group had 30 children, and cytokine levels were measured at baseline, months 3 and 6.

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serovar Newport is a human pathogen underreported in most developing countries. It is known for causing gastroenteritis and extraintestinal infections. In this case report, we report the case of ceftriaxone-resistant serovar Newport from South India, causing acute gastroenteritis in a sixty-year-old female patient having a history of antimicrobial therapy and recent hospital admission.

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Transformer is a well-known power system apparatus utilized in conjunction with solid insulations such as paper and press board, as well as liquid insulations like mineral oil, a petroleum-based fluid. Despite the notable drawbacks associated with mineral oil, such as limited resources for future generations and its non-eco-friendly nature, its usage remains ubiquitous. There is a growing imperative to explore alternative fluids that surpass mineral oil in terms of environmental impact and performance.

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Background: Kanikkaran are semi-nomadic tribes inhabiting Mundandhurai hills in Tamil Nadu. Their traditional method of maintaining oral health, seclusion, ignorance, and limited access to dental resources has led to their poor oral health situation. Thus, the present study is designed to assess the oral health status of the Kanikkaran tribals residing in Mundandhurai Hill of Tirunelveli district.

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