Publications by authors named "M Karkhaneh"

Background: Knowledge about the anatomy and morphology of the root canal system is essential for successful surgical and non-surgical root canal treatments. However, precise assessment of the root morphology and anatomy is not often possible on two-dimensional radiographs. This study aimed to investigate the association of root morphology of mandibular second molars on panoramic-like and axial views of cone-beam computed tomography (CBCT).

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Unlabelled: Timely diagnosis of hemophagocytic lymphohistiocytosis (HLH) is critical and relies on clinical judgment. The HLH-2004 criteria are commonly used diagnostic criteria, whereas HScore was recently developed for reactive HLH.

Objective: In this external validation study, we sought to compare the diagnostic accuracy of the HLH-2004 criteria and HScore and identify optimal cutoffs stratified by underlying etiology.

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Introduction: Improvements in haemophilia treatment over the last decades resulted in increased life expectancy in persons with haemophilia (PWH).

Aim: We conducted a systematic review and meta-analysis to examine all-cause mortality and causes of death among PWH.

Methods: We systematically searched EMBASE, MEDLINE, Web of Science, CINAHL and Cochrane central register of controlled trials from inception through March 15, 2021.

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Article Synopsis
  • Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a long-term illness characterized by severe fatigue, cognitive issues, and changes in sleep and bodily functions.
  • A systematic review was conducted to evaluate the effectiveness of mind-body interventions (MBIs) like mindfulness and relaxation techniques in treating ME/CFS symptoms in adults.
  • The review identified 12 relevant studies, showing that MBIs can lead to improvements in fatigue, anxiety/depression, and quality of life, although issues like small sample sizes and potential bias highlight the need for more standardized research in this area.
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Introduction: Administrative data is useful in population-based studies in hemophilia, but few studies validated the coding accuracy.

Aim: We validated the accuracy of a case definition using a combination of International Classification of Diseases diagnostic codes and coagulation factor level for identifying hemophilia in administrative data.

Methods: This is a retrospective population-based study of all residents of Alberta, Canada, who underwent testing for coagulation factor VIII (FVIII) or factor IX (FIX) activity between 2009 and 2017 using linked administrative data.

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