Background: Knowledge about the anatomy and morphology of the root canal system is essential for successful surgical and non-surgical root canal treatments. However, precise assessment of the root morphology and anatomy is not often possible on two-dimensional radiographs. This study aimed to investigate the association of root morphology of mandibular second molars on panoramic-like and axial views of cone-beam computed tomography (CBCT).
View Article and Find Full Text PDFUnlabelled: Timely diagnosis of hemophagocytic lymphohistiocytosis (HLH) is critical and relies on clinical judgment. The HLH-2004 criteria are commonly used diagnostic criteria, whereas HScore was recently developed for reactive HLH.
Objective: In this external validation study, we sought to compare the diagnostic accuracy of the HLH-2004 criteria and HScore and identify optimal cutoffs stratified by underlying etiology.
Introduction: Improvements in haemophilia treatment over the last decades resulted in increased life expectancy in persons with haemophilia (PWH).
Aim: We conducted a systematic review and meta-analysis to examine all-cause mortality and causes of death among PWH.
Methods: We systematically searched EMBASE, MEDLINE, Web of Science, CINAHL and Cochrane central register of controlled trials from inception through March 15, 2021.
Introduction: Administrative data is useful in population-based studies in hemophilia, but few studies validated the coding accuracy.
Aim: We validated the accuracy of a case definition using a combination of International Classification of Diseases diagnostic codes and coagulation factor level for identifying hemophilia in administrative data.
Methods: This is a retrospective population-based study of all residents of Alberta, Canada, who underwent testing for coagulation factor VIII (FVIII) or factor IX (FIX) activity between 2009 and 2017 using linked administrative data.