Publications by authors named "M Karaivanov"

Article Synopsis
  • Cervical cancer ranks as the fourth most common cancer in women globally, with squamous cell carcinoma (SCC) being the most prevalent type; a rare subtype of SCC is papillary squamotransitional cell carcinoma (PSCC), known for its aggressive nature and poor prognosis.
  • A case study of a 45-year-old woman with PSCC revealed symptoms like pelvic discomfort and widespread lymphadenopathy, leading to a confirmed diagnosis after various tests and imaging, indicating advanced cancer with metastasis.
  • The patient's situation highlights the challenges in diagnosing and treating PSCC, emphasizing its tendency to be discovered at advanced stages and the associated difficulties in management compared to typical SCC.
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We present you a Case of 62 year old man with Paratesticular leiomyosarcoma (LMS) localized to the right sctotal half. Detailed pathological and immunohistochemistry characteristic of the tumor was done. For staging was used the classification of French Federation of Cancer Centres Sarcoma Grading System.

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We present you a case of 43 year old man with classical form of Kaposi sarcoma (KS) localized to the Penis who was HIV negative. Detailed pathological and immunohistochemistry characteristic of the tumor was done. Pathology reported it as KS with nodular and polypoid form.

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The present study examines the expression of p63, glutathione S-transferase-pi (GSTP1) and alpha-methylacyl-CoAracemase (AMACR) in serial slices in proliferative inflammatory atrophy (PIA) in order to implicate that some of the basal cells are probably the putative human prostate carcinoma stem cells (PHPCSC). Archived tissue sections obtained after radical prostatectomy from cases (n=30) comprising of PIA were tested using immunohistochemistry with antibodies against AMACR (Dako), p63 and GSTP1 (Labvision) and visualized by biotin-streptavidin-peroxidase kit (DAKO LSAB 2 kit). Quantitative immunohistochemistry analysis (QIHC) of the studied antigen expression levels revealed that there are two populations of p63 basal cells.

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