Publications by authors named "M Kakegawa"
We report the magnetic properties of a cobalt oxalate metal-organic framework featuring the hyperoctagon lattice. Our thermodynamic measurements reveal the J_{eff}=1/2 state of the high-spin Co^{2+} (3d^{7}) ion and the two successive magnetic transitions at zero field with two-stage entropy release. ^{13}C-NMR measurements reveal the absence of an internal magnetic field in the intermediate temperature phase.
View Article and Find Full Text PDFAt present scintillation gamma camera plays key role in nuclear medicine as planner and tomographic single photon imaging modality. The basic technology of gamma camera made remarkable progress carried out by many researchers and engineers from around 1970 to 1980 and reached some matured stage as analog signal processing. Among them Dr.
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- This study investigates the effects of osimertinib, a targeted therapy, in elderly patients (≥75 years) with non-small cell lung cancer (NSCLC) who have specific mutations.
- Forty-three patients with adenocarcinoma were treated, showing a 60.5% overall response rate and a median progression-free survival (PFS) of 22.1 months.
- The treatment was generally safe with manageable side effects, but more research is needed to confirm these findings in a larger elderly population.
Article Synopsis
- - This study investigates the effectiveness and safety of osimertinib for treating poor performance status (PS) patients with EGFR-mutated non-small cell lung cancer (NSCLC) who have not received chemotherapy yet.
- - A total of 16 patients with specific EGFR mutations were treated, resulting in a 56.3% objective response rate and a median progression-free survival of 10.5 months, with half of the patients showing improvement in their PS score.
- - The treatment was generally well-tolerated, with common side effects being mild and only one case of interstitial lung disease reported, suggesting osimertinib is a promising option for this patient group, but larger studies are needed for confirmation. *
Background: Tokyo, the capital of Japan, is a densely populated city of >13 million people, so the population is at high risk of epidemic severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. A serologic survey of anti-SARS-CoV-2 IgG would provide valuable data for assessing the city's SARS-CoV-2 infection status. Therefore, this cross-sectional study estimated the anti-SARS-CoV-2 IgG seroprevalence in Tokyo.
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