Impact of Verbal Suggestions on Finger Flexor Activation and Strength in Healthy Individuals.

BACKGROUND Words uttered by other people can have an enormous influence on how we perceive our surroundings, what we expect, what we experience, and how we behave. This study aimed to evaluate the effect of verbal reinforcement on the placebo effect in the context of finger flexor muscle activation measured with surface electromyography (sEMG) and hand grip strength measured with a hand dynamometer in healthy subjects. MATERIAL AND METHODS Eighty-eight individuals aged 22.

Rare-variant association analysis reveals known and new age-related hearing loss genes.

Age-related (AR) hearing loss (HL) is a prevalent sensory deficit in the elderly population. Several studies showed that common variants increase ARHL susceptibility. Here, we demonstrate that rare-variants play a crucial role in ARHL etiology.

A monoallelic variant in EYA1 is associated with Branchio-Otic syndrome in a Malian family.

Background: Branchio-otic syndrome (BO) is one of the most common types of syndromic hearing impairment (HI) with an incidence of 1/40,000 globally. It is an autosomal dominant disorder typically characterized by the coexistence of branchial cysts or fistulae, malformations of the external, middle, and inner ears with preauricular pits or tags and a variable degree of HI. Most cases of BO have been reported in populations of European ancestry.

Exome sequencing of families from Ghana reveals known and candidate hearing impairment genes.

We investigated hearing impairment (HI) in 51 families from Ghana with at least two affected members that were negative for GJB2 pathogenic variants. DNA samples from 184 family members underwent whole-exome sequencing (WES). Variants were found in 14 known non-syndromic HI (NSHI) genes [26/51 (51.

Kinesiophobia in Elderly Polish Patients After Ischemic Stroke, Including Frailty Syndrome.

Introduction: In patients after stroke, the relationship between the occurrence of kinesiophobia and the accompanying frailty syndrome, as well as the acceptance of the disease and the level of mood, has not been recognized so far. The aim of this study was to determine the prevalence of kinesiophobia in elderly Polish people after ischemic stroke, including the frailty syndrome and the associations between the prevalence of kinesiophobia and feelings of anxiety and degree of the illness acceptance.

Methods: A cross-sectional study was used to achieve the study objectives.