Publications by authors named "M Kacprzak"
Article Synopsis
- The study investigates the effectiveness of whole exome sequencing in diagnosing genetic causes of epilepsy in adult patients in Poland, revealing a diagnostic yield of 8.6% using one classification method and 17% with another.
- A total of 151 adult patients from various clinical centers were analyzed, all previously diagnosed with epilepsy and lacking genetic diagnoses, and the research identified most variants linked to epilepsy-related genes.
- The findings suggest that whole exome sequencing is more effective than traditional gene panels and highlight the importance of considering genetic factors in adults with epilepsy, especially those showing early onset or developmental delays.
Article Synopsis
- The clinical use of diffuse optics (DO) in assessing brain injuries has faced challenges, such as inconsistent results from near-infrared spectroscopy devices and issues due to the complex nature of brain tissue.* -
- The study aimed to analyze how various tissue changes in injured brains affect DO signals and to provide guidelines to improve data interpretation.* -
- The findings highlighted the need for standardization in DO measurement practices to enhance its reliability in neurocritical care and emphasized the importance of rigorous quality control in the data collection process.*
Time-domain diffuse correlation spectroscopy (td-DCS) enables the depth discrimination in tissue's blood flow recovery, considering the fraction of photons detected with higher time of flight (TOF) and longer pathlength through the tissue. However, the recovery result depends on factors such as the instrument response function (IRF), analyzed TOF gate start time, gate width and the source-detector separation (SDS). In this research we evaluate the performance of the td-DCS technique at three SDSs of 1.
View Article and Find Full Text PDFTrees in cities perform important environmental functions: they produce oxygen, filter pollutants, provide habitat for wildlife, mitigate stormwater runoff, and reduce the effects of climate change, especially in terms of lowering temperatures and converting carbon dioxide from the atmosphere into stored carbon. Generally, to increase the environmental benefits of urban forests, the number of trees is increased, directly influencing the canopy coverage. However, little is known about potential of modifying the species composition of urban tree communities in order to increase ecological benefits.
View Article and Find Full Text PDFResearch on the spatial distribution of sensitivity of time-domain near infrared diffuse reflectance measurement is reported in this paper. The main objective of the investigation is to validate theoretically calculated sensitivity profiles for a measurement geometry with two detectors and two sources in which sensitivity profiles of statistical moments of distributions of time of flight of photons (DTOFs) are spatially restricted to a region underneath the detectors. For this dual subtraction method, smaller sensitivities to changes appearing in the superficial layer of the medium were observed compared to the single distance and single subtraction methods.
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