Publications by authors named "M K Zouaghi"

Introduction And Importance: Hydatidosis is a cosmopolitan zoonosis caused by larval stages of Echinococcus granulosus. The brain is a rare location for this disease to occur, especially in adults. The occipital location is extremely unusual and the cysts are usually solitary.

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Article Synopsis
  • - Alport syndrome is a genetic disorder impacting the kidneys, ears, and eyes, caused by mutations in specific COL4A genes, with varying inheritance patterns including X-linked and autosomal recessive.
  • - A study involving 45 patients from Tunisian families revealed 9 likely pathogenic variants, including 6 new ones, mostly in COL4A3 and COL4A5, and confirmed that many siblings tested positive for the condition.
  • - The findings indicate that autosomal recessive inheritance may be more prevalent in Tunisia than previously thought, marking the first comprehensive screening of Alport syndrome mutations in the region.
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The absolute necessity to fight some class of tumour is perceived as serious health concerns, and the discovery and development of effective anticancer agents are urgently needed. So, the novel benzimidazole derivatives () were designed, synthesized, with their structures rigorously characterized using single X-ray crystallography, FT-IR, UV, and NMR spectroscopy, alongside elemental analysis. The geometric structures were optimized using density functional theory (DFT) calculations performed at the ωB97X-D/cc-pVDZ level, yielding good agreement with experimental XRD data.

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Introduction: Longer survival in dialysis led to a higher incidence of vascular access complications and failure. With the limited access to kidney transplantation programs and peritoneal dialysis, exhaustion of vascular access for hemodialysis is an increasingly common situation. Among the available options, atrial tunneled dialysis catheter (ATDC) has been reported as an effective vascular access in this population.

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A new Schiff base, 1-(E)-(4-((E) 4nitrobenzylidene) amino) phenyl)imino) methyl)naphthalen-2-ol (4NMN), was prepared from the reaction of -phenylenediamine with 2-hydroxy-1-naphthaldehyde and 4-nitrobenzaldehyde and characterized with spectroscopic analysis. UV-VIS and NMR. Frontier molecular orbitals, molecular electrostatic potential, and chemical reactivity descriptors of the synthesized compound were studied using molecular modeling methods.

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