Publications by authors named "M K S Leow"

Healthy dietary patterns rich in legumes can improve metabolic health, although their additional benefits in conjunction with calorie restriction have not been well-established. We investigated effects of a calorie-restricted, legume-enriched, multicomponent intervention diet compared with a calorie-restricted control diet in 127 Chinese prediabetes participants, living in Singapore. The study was a 16-week, single-blind, parallel-design, randomized controlled trial (n = 63 intervention group (IG), n = 64 control group (CG); mean ± SD age 62.

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This study presents the "ESP32 Dataset," a dataset of radio frequency (RF) data intended for human activity detection. This dataset comprises 10 activities carried out by 8 volunteers in three different indoor floor plan experiment setups. Line-of-sight (LOS) scenarios are represented by the first two experiment setups, and non-line-of-sight (NLOS) scenarios are simulated in the third experiment setup.

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Background: Phenotypic age (PhenoAge), a widely used marker of biological aging, has been shown to be a robust predictor of all-cause mortality and morbidity in different populations. Existing studies on biological aging have primarily focused on individual domains, resulting in a lack of a comprehensive understanding of the multi-systemic dysregulation that occurs in aging.

Methods: PhenoAge was evaluated based on a linear combination of chronological age (CA) and 9 clinical biomarkers in 952 multi-ethnic Asian women of reproductive age.

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Article Synopsis
  • Current anti-obesity medications have limited effectiveness and side effects because they target the brain or digestive system, rather than directly addressing fat tissue.
  • This research presents a new therapy using Prussian blue nanoparticles applied through a skin patch that actively remodels white fat tissue, promoting weight loss and improved metabolism.
  • In tests on fat cells and obese mice, this therapy significantly reduced fat mass and improved metabolic health while showing promising safety outcomes, offering a potential new approach to treat obesity and related conditions like type 2 diabetes.
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