Publications by authors named "M K Raad"
Study Designs: Retrospective Database Analysis.
Objectives: Pre-operative glycemic control in diabetic patients undergoing lumbar fusion (LF) is essential for evaluating complication risk. However, current thresholds for preoperative HbA1c and same-day-glucose (SDG) are either non-specific or have low predictive power.
Background: Self-directed interventions are cost-effective for patients with cancer and their family caregivers, but barriers to use can compromise adherence and efficacy.
Aim: Pilot a Sequential Multiple Assignment Randomized Trial (SMART) to develop a time-varying dyadic self-management intervention that follows a stepped-care approach in providing different types of guidance to optimize the delivery of Coping-Together, a dyadic self-directed self-management intervention.
Methods: 48 patients with cancer and their caregivers were randomized in Stage 1 to: (a) Coping-Together (included a workbook and 6 booklets) or (b) Coping-Together + lay telephone guidance.
Background: Pacing-induced cardiomyopathy (PICM) is a frequent complication of right ventricular pacing that often requires reoperation for biventricular or conduction system pacing. Better methods for predicting PICM may inform initial pacing strategy and follow-up monitoring.
Objective: The purpose of this study was to determine whether the spatial ventricular gradient (SVG), a vectorcardiographic marker of ventricular electrical and mechanical heterogeneity, is associated with the subsequent development of PICM.
Waldenstrom macroglobulinemia (WM) is a non-Hodgkin B-cell lymphoma, characterized by bone marrow infiltration with plasma cells and lymphocytes. The tumor microenvironment (TME) plays an important role in mediating WM cell biology, but the effects of macrophages on WM biology remains unclear. Here, we investigated the effects of macrophages on WM growth and survival and identified a novel role for transcription factor GLI3 in macrophage polarization.
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- - Cancer remains a significant global health issue, with lung cancer being the leading cause of cancer-related deaths, alongside other respiratory cancers posing serious threats.
- - Natural killer (NK) cells, part of the immune system, are essential in fighting cancer, and their presence in tumors is linked to better survival rates, though cancer cells have ways to evade their attacks.
- - Advances in NK cell-based therapies, like CAR-NK cells and immune checkpoint inhibitors, show promise in treating respiratory cancers, yet challenges from the tumor microenvironment still need to be addressed through continued research.