Chitosan-grafted folic acid decorated one-dimensional GONS: A biocompatible drug cargo for targeted co-delivery of anticancer agents.

In conventional chemotherapy, the cancer cells can become highly resilient due to a phenomenon known as multi-drug resistance (MDR). The co-delivery of chemotherapeutic agents assisted with novel nanocarrier-based targeted DDS may counter the MDR issues and subsequently improve their therapeutic efficacy. In line with this, the present work deals with the development of 1D graphene oxide nanoscrolls (GONS)-based nano delivery system for co-delivery of chemosensitizer along with the chemotherapeutic agent.

Polycystic ovary syndrome and its management: In view of oxidative stress.

In the past two decades, oxidative stress (OS) has drawn a lot of interest due to the revelation that individuals with many persistent disorders including diabetes, polycystic ovarian syndrome (PCOS), cardiovascular, and other disorders often have aberrant oxidation statuses. OS has a close interplay with PCOS features such as insulin resistance, hyperandrogenism, and chronic inflammation; there is a belief that OS might contribute to the development of PCOS. PCOS is currently recognized as not only one of the most prevalent endocrine disorders but also a significant contributor to female infertility, affecting a considerable proportion of women globally.

Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization.

Tea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose. In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method. Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in white powdered form.

Synthesis of lignin from waste leaves and its potential application for bread packaging: A waste valorization approach.

In this study, lignin was synthesized from the waste leaves of Ficus auriculata obtained after the extraction of gallic acid. The synthesized lignin was incorporated into PVA films, and the neat and blended films were characterized using different techniques. Lignin addition improved the UV-shielding, thermal, antioxidant, and mechanical properties of PVA films.