Computational network analysis of two popular skin cancers provides insights into the molecular mechanisms and reveals common therapeutic targets.

Basal Cell Carcinoma (BCC) and Actinic Keratosis (AK) are prevalent skin conditions with significant health complications. The molecular mechanisms underlying these conditions and their potential shared pathways remain ambiguous despite their prevalence. Therefore, this study aims to elucidate the common molecular pathways and potential therapeutic targets for BCC and AK through comprehensive computational network analysis.

Comparing Antibody Responses to Homologous vs. Heterologous COVID-19 Vaccination: A Cross-Sectional Analysis in an Urban Bangladeshi Population.

Background: Vaccination has played a crucial role in mitigating the spread of COVID-19 and reducing its severe outcomes. While over 90% of Bangladesh's population has received at least one COVID-19 vaccine dose, the comparative effectiveness of homologous versus heterologous booster strategies, along with the complex interplay of factors within the population, remains understudied. This study aimed to compare antibody responses between these booster approaches.

Thematic analysis of perceptions from both patients and dental students on a digital clinical decision aid in prosthodontics: A qualitative study.

Objective: The present study aimed to investigate the impact of utilizing an innovative and comprehensive patient-centered digital clinical decision aid designed to facilitate shared decision-making in missing tooth replacement between dental students and their patients.

Methods: A qualitative study using interview approach was conducted in Hong Kong SAR and Malaysia. Thirty dental undergraduate students, each with one patient from the Faculty of Dentistry at The University of Hong Kong (n = 15) and Universiti Teknologi MARA (n = 15), were introduced to a digitally designed decision aid in missing tooth replacement prior to their treatment appointments.

Balance recovery and its link to vestibular agnosia in traumatic brain injury: a longitudinal behavioural and neuro-imaging study.

Background: Vestibular dysfunction causing imbalance affects c. 80% of acute hospitalized traumatic brain injury (TBI) cases. Poor balance recovery is linked to worse return-to-work rates and reduced longevity.

Anti-amyloid therapy and cerebral blood flow changes on Magnetic Resonance Imaging: a potential longitudinal biomarker of treatment response?

Amyloid-targeting therapy has recently become widely available in the U.S. for the treatment of patients with symptomatic mild Alzheimer's disease (AD).