Expression of GnRH, Kisspeptin, and Their Specific Receptors in the Ovary and Uterus in Deslorelin-Treated Late-Prepubertal Bitches.

In this study, the expression and localization of gonadotropin-releasing hormone (GnRH1) and kisspeptin (KISS1) and their specific receptors in canine ovarian and uterine tissues were investigated after the application of deslorelin acetate (Suprelorin, 4.7 mg, Virbac, France) in the late prepubertal period. We hypothesized that prolonged treatment of prepubertal dogs with deslorelin would alter the expression of GnRH and kisspeptin genes in the uterus and ovaries.

Comparison of Serum USP9x and TGF-β Levels in Children with Autism Spectrum Disorders with Healthy Controls.

Introduction: USP9X has been associated with neurodevelopmental disorders due to its role in synaptic development and neural function. This study aimed to compare USP9X and TGF-β levels in children with autism and healthy controls, and explore their relationship with autism severity.

Methods: Serum USP9X and TGF-β levels were measured in 41 healthy control children (aged 3-12 years) and 41 children with autism.

Orem's Self-Care Deficit Nursing Theory with Persons with Peripheral Artery Disease: A Mixed Method Study.

This study was conducted to determine the effects of an algorithm training booklet, which was based on Orem's self-care deficit nursing theory, specific to lower extremity peripheral artery disease, on pain, activities of daily living, self-care agency, walking distance, quality of life, and other symptoms. This mixed-method study included a qualitative stage using face-to-face in-depth individual interviews and a pretest-posttest semiexperimental design quantitative stage. In-depth interviews were conducted to highlight self-care needs and symptoms and to create the booklet.

Foot Reflexology for Pain and Anxiety Associated with Chest Tube Removal in Patients After Coronary Artery Bypass Graft: A Randomized Controlled Trial.

Background: Reflexology is a method used to control the pain and anxiety associated with chest tube removal in patients undergoing cardiovascular surgery.

Primary Study Objective: This study aimed to identify the effect of foot reflexology applied before chest tube removal on pain and anxiety levels in patients with coronary artery bypass graft surgery.

Methods/design: This study was a randomized controlled clinical trial.

Comparative Effects of Stimulant and Antipsychotic Medications on Eating Behaviors and Weight in Children with Attention Deficit Hyperactivity Disorder.

Background/objectives: Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with an increased risk of obesity and disordered eating behaviors. This study compared weight status and eating behaviors among drug-naïve ADHD children, those on stimulant monotherapy, those on combined stimulant and antipsychotic treatment, and healthy controls.

Methods: This cross-sectional study included 547 children aged 6-12 years from four Turkish provinces: 361 with ADHD (152 drug-naïve, 156 on stimulants, and 53 on combined therapy), and 186 healthy controls.