Formulation and evaluation of microsphere of antiulcer drug using gum.

Objective: This study was undertaken to evaluate the formulation of the microspheres for antiulcer drug using natural polymer gum.

Materials And Methods: All parameters evaluated gum, aqueous solution of purified gum was used for chemical characterization, organoleptic character, flow properties, pH, particle size determination, solubility, viscosity, surface tension, infrared spectroscopy, etc. The microspheres of famotidine were prepared by ionotropic gelation technique using cross-linking solution of aluminum chloride, barium chloride, and calcium chloride.