Characterization of alkaline phosphatase in polymorphonuclear neutrophils from normal sheep.

This paper is an attempt to the analysis of the main biochemical characteristics of alkaline phosphatase from sheep polymorphonuclear neutrophils. Ten male adult Romanoff X Berrichon sheep were studied. Alkaline phosphatase was analyzed from cell homogenates, after extraction and solubilization steps.

In vivo and in vitro effects of three glucocorticoids on blood leukocyte chemotaxis in the dog.

The effects of three glucocorticoids on random migration (RM) and oriented migration (OM) of dog blood leukocytes either from dogs treated in vivo (at therapeutic dosage regimen) or leukocytes treated in vitro (at pharmacological concentrations), were investigated using an agarose gel technique. After in vivo treatment, methylprednisolone sodium succinate (MPSS) produced a stimulation of both RM and OM in the three treated dogs. Dexamethasone produced a stimulation of both RM and OM in the three treated dogs.