Introduction And Objective: Proton pump inhibitor (PPI) use in children increases the risk of infections, prompting inquiry into the impact of prenatal PPIs exposure on serious infections in offspring. As a research gap in this area exists, this study aimed to address it by assessing the association between prenatal PPIs exposure and serious infections in infants during their first year of life.
Methods: Using the French health insurance data warehouse (SNDS) (2013-2018), we conducted a retrospective cohort study on singleton, full-term liveborn non-immunocompromised infants, stratified by PPI use during the first three months of life (early-life use).
Unlabelled: Intertwined within a patchwork of different types of land use and land cover, novel ecosystems are urban ecosystems that have no historical analogues and contain novel species assemblages. Some researchers and practitioners in the field of conservation and restoration regard urban novel ecosystems unworthy of concern, while other groups call for their preservation due to the rate of biodiversity loss in cities and limited access to nature among some social groups. However, very little is known about how people perceive novel ecosystems (such as informal green spaces, post-industrial or derelict land sites awaiting redevelopment, brownfield sites, vacant lots, interstitial or gap spaces) which are often characterised by assemblages of wild, spontaneous, and overgrown vegetation, but also remanent or derelict urban infrastructure in cities.
View Article and Find Full Text PDFBackground & Aims: There is limited understanding of the benefits of alcohol rehabilitation after alcohol hepatitis (AH).
Methods: We conducted a 2012 to 2021 national longitudinal study involving adult inpatients diagnosed with AH in France. We assessed the primary outcome of liver transplantation or death within 1 year after AH, including in its complicated form (CAH) defined as ≥2 hepatic or extrahepatic complications within 4 weeks after AH.