[Physiological role of pancreatic D-cells (mathematical study)].

The physiological role of pancreatic D cells has been studied by the method of mathematical simulation. D cells were proved to produce a sparing effect both on B and A cells, bringing about a more economical secretory response to these cells. The suppression of insulin secretion by pancreatic somatostatin is substantial at lower glucose concentration and is insignificant at higher glucose concentration.