Musculoskeletal disease in acromegaly - a population-based registry study.

Objective: Acromegaly is associated with multiple musculoskeletal complications that affect quality of life and work ability. We aimed to examine the risk of osteoarthritis, musculoskeletal surgery (incl. joint replacement), osteoporosis, fractures and analgesic consumption in Danish acromegaly patients.

Surgical management of metastatic lesions in the proximal femur: a systematic review.

Purpose: The proximal femur is a frequent site of cancer dissemination in the extremities. Patients treated surgically for skeletal metastases have poorer overall health compared to other orthopedic patients, with only one-third expected to survive two years post-surgery. Choosing a treatment that minimizes revision risk and ensures the implant outlives the patient is therefore crucial.

Family Involvement During Patient Hospitalisation-Developing and Testing a Clinical Decision Aid.

Background: The rising prevalence of multi-morbidity increases treatment complexity and caregiving demands, often necessitating involvement of family members as informal caregivers. While essential, this involvement can be burdensome, causing distress for family members. Shared decision-making facilitates communication and supports the alignment of patients' and families' preferences and needs with care and treatment decisions.

Genetic determinants of muscle health: A population-based study.

Background: Muscle mass is associated with physical and functional performance across adulthood. Its reduction plays a crucial role in the development of age-related conditions such as frailty and sarcopenia. Genetic variations potentially impact muscle health, particularly in an aged population.