The association between primary sclerosing cholangitis (PSC) and microscopic colitis (MC) has been explored in limited studies, suggesting potential shared pathophysiological mechanisms. This systematic review aimed to investigate this relationship by analyzing studies identified through comprehensive searches in PubMed, Embase, and the Cochrane Library. Two studies met the inclusion criteria: a case series of 12 patients and a case report, collectively analyzing 13 cases.
View Article and Find Full Text PDFResearch for novel compounds that may block bacterial development has continued and prompted by antibiotic-resistant bacteria. The expenses of community for health care as a result of antibiotic resistance has indeed been remarkable during the last decades and demand immediate of medical attention. Consequently, this research presents the antibacterial effect of genuine metal oxide nanoparticles against () and that have been isolated from urinary tract infection patients.
View Article and Find Full Text PDFSpontaneous pneumothorax usually presents with sudden chest pain and dyspnea as cardinal symptoms, but its diagnosis may be challenging with atypical presentation. We describe here the case of an unusual presentation of spontaneous pneumothorax in a 20-year-old male nonsmoker with no past medical history, presenting to the emergency department with intense back pain accompanied by vomiting. The diagnosis of spontaneous pneumothorax should be entertained by the clinicians, even in atypical presentations, for timely management.
View Article and Find Full Text PDFThis review investigates the pathogenic processes through which crosses the blood-brain barrier (BBB) to cause meningitis, with a focus on the interaction with host receptors in the central nervous system (CNS). a primary cause of bacterial meningitis, utilizes unique receptor-mediated pathways to infiltrate the BBB. The bacterial interaction with the platelet-activating factor receptor (PAFR) and the polymeric immunoglobulin receptor (pIgR) is looked at in this study.
View Article and Find Full Text PDFParkinsonism, commonly associated with Parkinson disease (PD), can also arise from other neurodegenerative disorders or non-neurodegenerative causes such as vascular parkinsonism (VP). This case highlights the acute onset of VP following a stroke, contributing to the understanding of VP's varied presentations and the challenges in its diagnosis. A 54-year-old male with a history of cerebrovascular disease presented with behavioral changes and reduced activity, initially raising the suspicion of a central nervous system infection.
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