Publications by authors named "M K A Schutt"
Article Synopsis
- Dysphagia, a serious swallowing disorder, is common in patients with advanced Parkinson's disease (PD) and doesn’t improve with standard treatments.
- This study tested whether combining stimulation of the subthalamic nucleus (STN) and substantia nigra pars reticulata (SNr) could enhance swallowing function in 20 PD patients undergoing deep brain stimulation (DBS).
- Results showed no significant difference in swallowing improvements between the two stimulation methods, but overall, all patients experienced better outcomes over eight weeks, likely due to ongoing swallowing therapy and increased focus on their swallowing abilities.
Background: We present a digital therapeutic (DTx) using continuous glucose monitoring (CGM) and an advanced artificial intelligence (AI) algorithm to digitally personalize lifestyle interventions for people with type 2 diabetes (T2D).
Method: A study of 118 participants with non-insulin-treated T2D (HbA ≥ 6.5%) who were already receiving standard care and had a mean baseline (BL) HbA of 7.
This study investigates HLA-DR expression on activated T cells and serum neopterin levels in Juvenile Dermatomyositis (JDM) children pre- and post-treatment. Sixty-nine JDM children (less than 18 years) were included. Elevated HLA-DR+ cells (>7 %) were observed in 19 % of untreated cases.
View Article and Find Full Text PDFBackground: Despite the availability of effective treatments, most depressive disorders remain undetected and untreated. Internet-based depression screening combined with automated feedback of screening results could reach people with depression and lead to evidence-based care. We aimed to test the efficacy of two versions of automated feedback after internet-based screening on depression severity compared with no feedback.
View Article and Find Full Text PDFArticle Synopsis
- Spinal muscular atrophy (SMA) is a genetic disease causing muscle weakness; gene replacement therapy (GRT) is one treatment but can affect the heart, making cardiac monitoring essential.
- This study collected high-sensitive cardiac troponin I (hs-cTnI) levels from 30 newborns with SMA and compared them to 16 without SMA to establish baseline values.
- Results showed neonates with SMA had higher hs-cTnI levels than adult reference values, indicating the need for careful monitoring of these levels before and after GRT treatment.