Publications by authors named "M Juvany"
Objectives: To evaluate the knowledge of abdominal wall closure in a cohort of specialist general surgeons who are members of the AEC and to see its adequacy with current recommendations. Sub-analysis in terms of years of specialization.
Material And Methods: Individual questionnaire of 21 questions on abdominal wall closure in elective and urgent context.
Article Synopsis
- Surgical site infections (SSI) are a common issue following surgeries, particularly in incisional hernia repairs, and the effectiveness of topical antibiotics like gentamicin for prevention remains uncertain.
- A randomized controlled trial was conducted with 146 patients, comparing outcomes between those given a gentamicin solution and those given saline solution during surgery.
- The study found no significant differences in SSI rates or other complications between the two groups, indicating that topical gentamicin did not effectively reduce SSI incidence in hernia repair surgeries.
Background: While selective use of antibiotics for infected pancreatic necrosis (IPN) in acute pancreatitis (AP) is recommended, studies indicate a high rate of inadequate treatment.
Methods: A search of PubMed, Scopus, and Cochrane databases was conducted, focusing on primary research and meta-analyses. Data were categorized based on core concepts, and a narrative synthesis was performed.
Article Synopsis
- - A multicentre cohort study analyzed the effectiveness of two surgical site infection prevention protocols in elective colorectal surgery, finding a significant reduction in infection rates from 18.16% down to 8.19% after implementing the bundles consecutively.
- - Bundle-2 specifically led to a decrease in superficial and deep surgical site infections and improved compliance with the additional measures included, while the length of hospital stays and mortality rates also decreased significantly.
- - The study highlighted protective factors for organ/space surgical site infections in colonic procedures and noted a shift in bacterial isolates, showing an increase in Gram-positive bacteria and a decrease in Gram-negative bacteria.
Glutamine and glutamate are interconverted by several enzymes and alterations in this metabolic cycle are linked to cardiometabolic traits. Herein, we show that obesity-associated insulin resistance is characterized by decreased plasma and white adipose tissue glutamine-to-glutamate ratios. We couple these stoichiometric changes to perturbed fat cell glutaminase and glutamine synthase messenger RNA and protein abundance, which together promote glutaminolysis.
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