Publications by authors named "M Jozwik"

Background: Dermatofibrosarcoma protuberans (DFSP) is a rare proliferative condition representing skin sarcomas known to locally recur yet very rarely known to metastasize. A typical characteristic is trunk localization, making vulvar occurrences an exception. Complete resection is the primary treatment.

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: In endometriosis, urinary tract involvement occurs in 1-5.5% of cases, where the ureter is affected in 9-23%. Unfortunately, endometriosis may remain asymptomatic even with significant anatomical progression.

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Article Synopsis
  • Large field-of-view (FOV) microscopic imaging is crucial in biomedicine, particularly in label-free techniques like lensless digital holographic microscopy (LDHM), which offers high resolution but faces challenges in accurate quantitative phase imaging (QPI).
  • The research uses two-photon polymerization (TPP) to create widefield phase test targets, enabling the assessment of LDHM's imaging errors across the entire large FOV under various conditions.
  • Results showed that there are minimal phase value differences (under 12%) near the detector's edges, highlighting the need for new design approaches in photonic manufacturing to improve large-area lensless imaging accuracy.
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Endometrial cancer (EC) is the most common gynecological malignancy. EC is associated with metabolic disorders that may promote non-enzymatic glycation and activate the receptor for advanced glycation end-products (RAGE) signaling pathways. Thus, we assumed that RAGE and its ligands may contribute to EC.

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Article Synopsis
  • Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer that tends to grow locally but rarely spreads to other parts of the body; its treatment primarily involves complete surgical removal.
  • The condition is linked to a specific genetic mutation, and its prognosis varies significantly between low-to-moderate grade DFSP and high-grade fibrosarcomatous DFSP, the latter having a worse outlook.
  • Several factors, such as tumor size, surgical margins, and patient age/gender, influence the risk of recurrence and metastasis, underscoring the importance of careful monitoring and management strategies, particularly for more aggressive cases.
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