Publications by authors named "M Jovicevic Klug"

Background: Handgrip strength (HGS) is an excellent marker of general strength capacity and health among adults. We aimed to calculate temporal trends in HGS for adults from Shanghai between 2000 and 2020.

Methods: Adults aged 20-59 years from Shanghai, China, were included.

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Article Synopsis
  • Muscular strength, particularly measured by handgrip strength (HGS), is an important indicator of health and a predictor of age-related diseases, but no international benchmarks exist for HGS across different ages and sexes.
  • The study systematically analyzed data from over 2.4 million adults across 69 countries to establish sex- and age-specific norms for HGS, identifying a peak in strength between ages 30 and 39 before a gradual decline.
  • Findings revealed that while absolute and body size-normalized HGS improves slightly in early adulthood, a more significant drop occurs from middle to late adulthood, with males generally experiencing a faster decline than females.
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Oxytocin (OT) is a neuropeptide produced in the paraventricular (PVH) and supraoptic (SON) nuclei of the hypothalamus. Either peripheral or central administration of OT suppresses food intake through reductions in meal size. However, pharmacological approaches do not differentiate whether observed effects are mediated by OT neurons located in the PVH or in the SON.

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This study aims to identify common contaminants in well water linked to an increase in colorectal cancer (CRC) incidence rates in North Dakota (ND) counties. County-specific incidence rates for CRC were obtained from the ND Statewide Cancer Registry. Corresponding demographic, agricultural, and geophysical data were obtained from population-based sources.

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