Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics.

Background/objectives: The role of the gut microbiome in cancer biology has become an increasingly prominent area of research, particularly regarding the role of microbial metabolites and their receptors (MMRs). These metabolites, through the various gut-organ axes, have been proven to influence several pathogenetic mechanisms. This study conducted a comprehensive pan-cancer analysis of MMR transcriptomic profiles across twenty-three cancer types, exploring the mechanisms through which they can influence cancer development and progression.

The 2023 fatal dengue outbreak in Bangladesh highlights a paradigm shift of geographical distribution of cases.

In 2023, Bangladesh experienced its largest and deadliest outbreak of the Dengue virus (DENV), reporting the highest-ever recorded annual cases and deaths. Historically, most of the cases were recorded in the capital city, Dhaka. We aimed to characterize the geographical transmission of DENV in Bangladesh.

Synergy of Hydrophilic Properties and Antibacterial Inhibition in Polyvinyl Alcohol Nanofibrous Mats Loaded With Croton Bonplandianum Baill Leaf Extract.

The antibacterial nanofibrous mat is crucial in biomedicine as it enhances infection control, expedites wound healing, and mitigates health hazards by decreasing antibiotic usage. A novel synergistic antibacterial and hydrophilic nanofibrous mat successfully fabricated by solution electrospinning from polyvinyl alcohol (PVA) incorporated Croton bonplandianum Baill (CBB) leaves extract. Antioxidant-enriched leaf extract of the CBB plant was integrated with PVA in varying proportions of 30% (CBB-30), 40% (CBB-40), and 50% (CBB-50) to manufacture antibacterial nanofibrous mat.

Application of enhances salt tolerance and yield of Indian mustard through increasing antioxidant enzyme activity.

Growth and yield reduction of crops due to salt stress have become a serious issue worldwide. is very well known as a plant growth-promoting fungi under abiotic stress conditions. Therefore, this study was designed to investigate the effect of on the growth, yield, nutrient uptake, and antioxidant activity of three Indian mustard genotypes under saline condition (EC 9.

Nitroxide radical contrast agents for safe magnetic resonance imaging: progress, challenges, and perspectives.

Magnetic resonance imaging (MRI) is considered one of the most valuable diagnostic technologies in the 21st century. To enhance the image contrast of anatomical features, MRI contrast agents have been widely used in clinical MRI diagnosis, especially those based on gadolinium, manganese, and iron oxide. However, these metal-based MRI contrast agents show potential toxicity to patients, which urges researchers to develop novel MRI contrast agents that can replace metal-based MRI contrast agents.