Mycotoxigenic fungi, OTA and fumonisin B2 production by Aspergillus section Nigri isolated from wine grapes and natural occurrence of OTA in wines of Northern Argentinean Patagonia.

The Northern Argentinean Patagonia is the southernmost producing region of wine grapes and wine in Argentina. Their wines possess distinctive features due to the wide variety of red and white grapes and weather conditions, achieving great acceptance in local and international markets. The aims of the present study were to determine and characterize the mycobiota present in wine grapes from Northern Patagonia, to analyse the ability of the isolates to produce mycotoxins, and to determine the natural occurrence of OTA and monitoring its presence in wine over time.

Consequences of Early Maternal Deprivation on Neuroinflammation and Mitochondrial Dynamics in the Central Nervous System of Male and Female Rats.

Early life stress (ELS) is associated with an increased risk for neuropsychiatric disorders, and both neuroinflammation and mitochondrial dysfunction seem to be central to mental health. Herein, using an animal model of ELS, a single episode of maternal deprivation (MD, 24 h on pnd 9) extensively documented to elicit behavioural anomalies in male and female Wistar rats, we investigated its consequences in terms of neuroinflammation and mitochondrial dynamics in the prefrontal cortex (PFC) and the hippocampal formation (HCF). MD differentially affected the brain content of cytokines: MD induced a transient increase in pro-inflammatory cytokines (IL-1β and IL-6) in the PFC, as well as in the levels of the anti-inflammatory cytokine IL-10 in the HCF.

Assessment of chemical risks and benefits connected with macroalgae consumption.

Reducing animal-based food production and consumption due to environmental issues and undergoing upcoming changes in food dietary patterns is pushing European society to search for new protein sources. Consuming macroalgae (seaweed) is one of the possible solutions, and it is an exciting alternative for both sustainability and consumers' health. The aim of this work, implemented under the EU-FORA fellowship programme, was to evaluate the current and projected consumption of macroalgae in terms of possible beneficial and detrimental effects on consumers.

Coordination geometry flexibility driving supramolecular isomerism of Cu/Mo pillared-layer hybrid networks.

Hydrothermal synthesis led to four novel 3D pillared-layer metal-organic frameworks: [Cu(4,4'-bipy)(MoO)·0.3HO] (1), [Cu(4,4'-bipy)(MoO)·0.25HO] (2), [Cu(4,4'-bipy)(MoO)·0.

Predictors of End-of-Life Care in Nonelderly Adults With Severe Traumatic Brain Injury.

Introduction: Older age is a well-established risk factor for withdrawal of life-sustaining therapy (WDLST) and discharge to hospice (DH) in traumatic brain injury (TBI). However, a paucity of data exists in identifying factors associated with end-of-life (EoL) care in younger patients with TBI. We sought to identify hospital and patient factors associated with EoL care and timing of EoL care in younger adults with severe TBI.