Publications by authors named "M Jose Carpio"

Article Synopsis
  • The rising rates of diabetes mellitus, especially type 2 diabetes (T2D), present major public health issues, particularly due to diabetic kidney disease (DKD) being a severe consequence.
  • Research highlights how macrophages, a type of inflammatory cell, play a crucial role in the onset and progression of DKD linked to obesity-related T2D.
  • By targeting macrophage activation, new therapies could potentially help manage DKD at various stages of its progression, showing promise for improving patient outcomes.
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Idiopathic pulmonary fibrosis (IPF) is a severe form of pulmonary fibrosis. IPF is a fatal disease with no cure and is challenging to diagnose. Unfortunately, due to the elusive etiology of IPF and a late diagnosis, there are no cures for IPF.

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Background: Alarm fatigue in nurses is a major patient safety concern in the intensive care unit. This is caused by exposure to high rates of false and non-actionable alarms. Despite decades of research, the problem persists, leading to stress, burnout, and patient harm resulting from true missed events.

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Osteopontin (OPN) is a ubiquitously expressed protein with a wide range of physiological functions, including roles in bone mineralization, immune regulation, and wound healing. OPN has been implicated in the pathogenesis of several forms of chronic kidney disease (CKD) where it promotes inflammation and fibrosis and regulates calcium and phosphate metabolism. OPN expression is increased in the kidneys, blood, and urine of patients with CKD, particularly in those with diabetic kidney disease and glomerulonephritis.

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The satisfaction of clients/owners, though very important as a determinant of construction project performance, has often been given very little attention in pro-environmental-related studies. To this end, this study's aim is to determine how owner's satisfaction (OS) can be realized via health and safety performance (HSP) and economic performance (EP) on construction projects that adopt pro-environmental construction practices (PCP) in Nigeria and to determine how the impact of HSP on OS can vary contingent on the level of EP. This study's aim was realized through data obtained from a survey of 249 construction projects and analyzed by adopting the partial least squares structural equation modeling (PLS-SEM) technique.

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