Comparison of Binary Alcohol/Water Solvent Systems to Blood for Extractions of Blood-Contacting Medical Devices.

The analysis of extractables and leachables and subsequent risk assessment is an important aspect of the determination of biocompatibility for many medical devices. Leachable chemicals have the potential to pose a toxicological risk to patients, and therefore it is required that they be adequately characterized and assessed for potential safety concerns. One important consideration in the assessment of leachables is the choice of a suitable simulating solvent intended to replicate the use condition for the device and its biological environment.

Comparison of the Accuracy and Reliability of Instrumental Shade Selection Devices and Visual Shade Selection: An in Vitro Study.

Objective: New shade-matching devices are available for clinical use, but their accuracy and reliability have not been investigated. This in vitro study compared the accuracy and reliability of a shade-matching colorimeter (Optishade), a spectrophotometer (VITA Easyshade V), and visual shade matching in simulated clinical conditions.

Material And Methods: Shade matching was conducted with two digital devices; (Optishade and Vita Easyshade) and the visual shade selection method, with a new 16-tab Vita Classical shade guide.

Hiding Assistive Robots During Training in Immersive VR Does Not Affect Users' Motivation, Presence, Embodiment, Performance, Nor Visual Attention.

Combining immersive virtual reality (VR) using head-mounted displays (HMDs) with assisting robotic devices might be a promising procedure to enhance neurorehabilitation. However, it is still an open question how immersive virtual environments (VE) should be designed when interacting with rehabilitation robots. In conventional training, the robot is usually not visually represented in the VE, resulting in a visuo-haptic sensory conflict between what users see and feel.

An Analytical Strategy Based on Multiple Complementary and Orthogonal Chromatographic and Detection Methods (Multidetector Approach) to Effectively Manage the Analytical Evaluation Threshold (AET).

To address patient safety, a drug product is chromatographically screened for organic leachables. Similarly, medical device and packaging system extracts are chromatographically screened for organic extractables as probable leachables. To protect patient health, the screening methods must respond to all potentially unsafe substances.