Publications by authors named "M Joest"
This article is an abridged version of the updated AWMF mould guideline "Medical clinical diagnostics in case of indoor mould exposure - Update 2023", presented in July 2023 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with German and Austrian scientific medical societies, and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established. There is no evidence for a causal relationship between moisture/mould damage and human diseases, mainly because of the ubiquitous presence of fungi and hitherto inadequate diagnostic methods.
View Article and Find Full Text PDFHypersensitivity pneumonitis (HP) is an immune-mediated interstitial lung disease (ILD) in sensitized individuals caused by a large variety of inhaled antigens. The clinical form of acute HP is often misdiagnosed, while the chronic form, especially the chronic fibrotic HP, is difficult to differentiate from other fibrotic ILDs. The present guideline for the diagnosis and treatment of HP replaces the former German recommendations for the diagnosis of HP from 2007 and is amended explicitly by the issue of the chronic fibrotic form, as well as by treatment recommendations for the first time.
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Article Synopsis
- Interstitial lung diseases (ILD) are diverse, chronic conditions affecting the lungs, with up to 50% of patients experiencing progression associated with higher mortality rates.
- The EXCITING-ILD registry analyzed disease trajectories, categorizing progression levels based on forced vital capacity (FVC) changes and identifying risk factors for progression through statistical models.
- Out of 601 patients, 50.6% showed progression, with median survival after diagnosis at 15.5 years, while reduced baseline FVC and older age were identified as key predictors of disease progression and shorter survival times.
Article Synopsis
- The International Society for Human and Animal Mycology (ISHAM) has updated guidelines for managing allergic bronchopulmonary aspergillosis (ABPA) and allergic bronchopulmonary mycosis (ABPM) due to improvements in diagnostic and therapeutic methods.
- An expert group utilized a modified Delphi method to reach a consensus on the recommendations, which include screening practices and diagnostic criteria for ABPA and ABPM in both adults and children.
- Key recommendations include routine screening for fungal sensitization in specific patient groups, clear diagnostic criteria for ABPA and ABPM, and suggested treatments such as oral prednisolone or itraconazole for acute cases, while noting that asymptomatic ABPA patients do not require treatment.