Publications by authors named "M Jimenez-Toscano"

Purpose: To address the educational gaps and support needs of patients with low anterior resection syndrome (LARS) following rectal cancer surgery. The LARSCAT project aimed to develop comprehensive resources to better inform patients and enhance their quality of life.

Methods: A qualitative study was conducted between November 2022 and March 2023.

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Purpose: To better understand immigration disparities among a Spanish Early-Onset Colorectal Cancer (SECOC) subset, according to the country of origin.

Patients And Methods: We selected 250 consecutive participants from the SECOC consortium. Data on baseline patient and tumor characteristics, family history of colorectal cancer (CRC), and follow-up were collected.

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Article Synopsis
  • Early detection of postoperative complications in colorectal cancer surgery can improve patient outcomes, and this study aims to identify metabolic signatures that indicate risk for severe complications.
  • Researchers analyzed plasma samples from 146 patients before and after surgery, using mass spectrometry to identify 188 metabolites and their ratios, finding significant associations between metabolic changes and the severity of complications.
  • Key findings showed that specific metabolite ratios, particularly kynurenine/tryptophan and lysophosphatidylcholines, could predict a patient's risk for major complications, potentially guiding early intervention strategies to enhance surgical outcomes.
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Early-onset colorectal cancer (EOCRC; age younger than 50 years) incidence has been steadily increasing in recent decades worldwide. The need for new biomarkers for EOCRC prevention strategies is undeniable. In this study, we aimed to explore whether an aging factor, such as telomere length (TL), could be a useful tool in EOCRC screening.

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