The Role of Pathogens in Bumblebee Decline: A Review.

Bumblebees, the most important wild pollinators in both agricultural and natural ecosystems, are declining worldwide. The global decline of bumblebees may threaten biodiversity, pollination services, and, ultimately, agricultural productivity. Several factors, including pesticide usage, climate change, habitat loss, and species invasion, have been documented in the decline of bumblebee species, but recent studies have revealed the dominating role of pathogens and parasites over any of these causes.

[Hematopoietic Transplantation Outcomes in Patients with HLA-Identical, Haploidentical, and Unrelated Donors at a University Hospital in Chile].

Unlabelled: Allogeneic transplantation (HSCT) is a curative option for several hematological diseases. Our center has privileged the use of identical family donors (IFD) or haploidentical (HD) donors. However, the chances of finding family donors may be challenging in small families or unsuitable donors.

Chemometrics and digital image colorimetry approaches applied to paper-based analytical devices: A review.

Colorimetric paper-based analytical devices (CPADs) are cost-efficient and high-throughput technologies that use readily available materials for point-of-need (PON) applications by leveraging color changes in response to target analytes. However, the complexity of samples can limit the precision and accuracy of CPAD applications. Therefore, CPADs have been combined with chemometric approaches to enhance analytical performance and provide simple solutions to complex systems.

Elacestrant in women with estrogen receptor-positive and HER2-negative early breast cancer: results from the preoperative window-of-opportunity ELIPSE trial.

Introduction: Elacestrant has shown significantly prolonged progression-free survival compared to standard-of-care endocrine therapy in estrogen receptor-positive (ER-positive), HER2-negative metastatic breast cancer (BC), while potential benefit in early-stage disease requires further exploration. The SOLTI-ELIPSE window-of-opportunity trial investigated the biological changes induced by a short course of preoperative elacestrant in postmenopausal women with early BC.

Methods: Eligible patients with untreated T1c (≥1.

Dispersal promotes stability and persistence of exploited yeast mutualisms.

Multi-species mutualistic interactions are ubiquitous and essential in nature, yet they face several threats, many of which have been exacerbated in the Anthropocene era. Understanding the factors that drive the stability and persistence of mutualism has become increasingly important in light of global change. Although dispersal is widely recognized as a crucial spatially explicit process in maintaining biodiversity and community structure, knowledge about how the dispersal of mutualists contributes to the persistence of mutualistic systems remains limited.