Publications by authors named "M Jayahar Bharathi"

An assessment of the anticancer activity of Glutaraldehyde-crosslinked Naringenin-loaded Albumin Nanoparticles (GNANPs) against gastric cancer cells was the purpose of this study. The increasing prevalence of gastric cancer and the limitations of conventional therapies necessitate novel approaches that combine targeted drug delivery with therapeutic efficacy. Several techniques were used to characterize the synthesized GNANPs, including UV-visible spectroscopy, X-ray diffractometer (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), Fourier transform infrared (FT-IR), dynamic light scattering (DLS), and photoluminescence (PL).

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Purpose: To compare glaucoma suspects' 24-hour blood pressure pattern with healthy subjects and the Retinal Nerve Fibre Layer (RNFL) thickness among dippers and non-dippers.

Materials And Methods: We included 100 patients diagnosed as glaucoma suspects in the study group and 100 age and gender-matched controls. Twenty-four-hour ambulatory blood pressure (BP) was measured using an automated BP monitoring device for mean systolic BP (SBP), mean diastolic BP (DBP), and mean arterial pressure (MAP).

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Purpose: Surface-altered, targeted nanocarriers play crucial roles in chemotherapy. Incorporating ligands into polymers may alter their chemical composition, potentially compromising their drug storage and encapsulation capacity. Polydopamine (PDA) is a novel, biocompatible, and versatile agent for producing targeted nanoparticles that serve as a base for conjugating specific ligands to non-reactive polymeric nanocarriers.

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A bio-fabrication approach is a novel way to develop chitosan-stabilized magnesium oxide nanomaterials (cMgO-NMs). The process involves utilizing polymeric chitosan as the reducing and stabilizing agent. The characteristics of the developed cMgO-NMs were determined using various spectroscopical techniques.

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The study synthesized Pluronic F-127 coated zinc oxide nanoparticles (PF-127ZnO NPs) using leaf extract and evaluated their antibacterial, antioxidant, and anticancer properties using various characterization methods such as UV-Vis, Fourier Transform Infra-Red, Photoluminescence spectroscopy, FESEM, EDAX, TEM, SAED, XRD, and DLS. The disc diffusion technique was used to evaluate the antibacterial properties of synthesized Pluronic F-127 coated zinc oxide nanoparticles against various pathogens and significant anticancer activity was noticed. The study examined the cytotoxicity of PF127ZnO nanoparticles to Hep3B cells .

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